We are pleased to share a new publication from the HiELuVent project, the sister project of BioMembrOS, titled “Effects of Pulsatile Bi-level Ventilation on Flow Characteristics in an Alveolated Duct: A Comparative Study”, published in Computers in Biology and Medicine.
The study is part of the FFG BRIDGE project HiELuVent, a collaboration between TU Wien and Carl Reiner GmbH.
Using Computational Fluid Dynamics (CFD) combined with Fluid–Structure Interaction (FSI) and realistic experimental boundary conditions, the researchers compared airflow behavior in a single alveolated duct during Bi-level Ventilation (BLV) and Pulsatile Bi-level Ventilation (PBLV).
Their findings show that PBLV produces more dynamic and complex flow patterns, including transient vortices and three-dimensional spiral structures, which may enhance air mixing and gas exchange. In contrast, BLV results in a more stable and less recirculating flow.
These insights provide a deeper understanding of the aerodynamic mechanisms behind advanced ventilation modes and support the development of more efficient artificial respiration strategies.
Read the full article here: Effects of Pulsatile Bi-level Ventilation on flow characteristics in an alveolated duct: A comparative study, opens an external URL in a new window
DOI: 10.1016/j.compbiomed.2025.110509, opens an external URL in a new window