Transforming bioscience into innovative applications for health, industry, and sustainability

 

We study how biological systems can be harnessed for sustainable production and environmental protection. Our research covers microbial systems, biosynthetic pathways, and bioinformatic supported “omic” approaches as foundations for biotechnological applications. We investigate processes for producing organic acids, enzymes, and bioactive compounds, while developing molecular diagnostic tools for water quality and microbiome assessment. This diversity of approaches allows us to connect bioscience with practical technological solutions.

We aim to transform biological insights into products and processes that serve society. From bio-based concrete to whole-cell biocatalysts, our work contributes to new materials, cleaner water, and more affordable medicines. We emphasize efficiency, environmental compatibility, and innovation — driving the next generation of biotechnology for health, industry, and sustainability.
 

E166-05-1 - Molecular Biology and Bioinformatics

A colorful, funny drawing of a seated dinosaur looking at a strand of DNA from a test tube. A thought bubble with a question mark hovers above the dinosaur.

© Yuriy Karpenko

Our research aims to ensure the availability of essential products, promote sustainable production processes and contribute to the reduction of CO₂ emissions. To this end, we are developing microbial solutions for enzyme production, improving the durability of concrete and identifying new secondary metabolites from fungi. We combine molecular and mycological approaches with DNA/RNA-based omics technologies to investigate regulatory networks and epigenetic mechanisms in fungi. On this basis, we develop high-performance production strains of Trichoderma and Aureobasidium.

E166-05-2 - Biochemistry

Gruppenphoto

© Sebastian Philipp

The biochemistry group at TU Wien uses the metabolic potential of microorganisms to enable the sustainable production of valuable bio-based chemicals as part of the biorefinery concept. In the process, renewable raw materials are converted into products such as organic acids, proteins and alcohols. By combining basic and applied research, we optimize microbial metabolic pathways using modern methods such as CRISPR/Cas9, single-cell analyses and adaptive evolution. Industrial host organisms such as Aspergillus niger, Komagataella phaffii and Saccharomyces cerevisiae are used.

E166-05-3 - Microbiology and Molecular Diagnostics

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© FG Microbiology and Molecular Diagnostics

A leader in molecular microbial diagnostics for the challenges of tomorrow. A particular focus of the research group is the development, evaluation, and application of DNA-/RNA-based diagnostic methods to support targeted and evidence-based management of water quality for human use (drinking water, climate change-resilient water safety planning, bathing waters, irrigation, reuse, recreation, water hygiene).