Laboratory and equipment

Unser Labor ist mit einer breiten Palette von Instrumenten für theoretische und experimentelle Untersuchungen von Bioflüssigkeiten und Hilfsgeräten für menschliche Organe ausgestattet.

This fully instrumented  mock circulation was developed for assessment of the performance of an axial flow, pneumatically operated left ventricular assist device (LVAD). Due to a high degree of flexibility and a wide range of hemodynamic states that can be simulated, the mock circulation is suitable for in-vitro experiments with various assistive devices being developed for support of the cardiovascular system.

Diagram example test circuit
Mock circulation test setup

Main functions of the fully instrumented test loops are

  • assessment of mass transfer and pressure drop in membrane contactors
  • determination of characteristic flow-pressure curves of blood pumps
  • assessment of hemolysis caused by assist devices
Example test circuit structure
Set-up plan test circuit

  

A Researcher preparing a sample for measurements with the Micro PIV

We use a TSI Micron Resolution Particle Image Velocimeter for measuring flows in microchannels based on an inverted microscope with flow field in a size range from <100 micron to 2mm, and 80nm-1micron imaging resolution per pixel in combination with a powerful compact Dual Cavity Laser.

Micro PIV System
Results of a Micro PIV measurment

High accuracy digital microscope capable of capturing high resolution images and measurement data for inspection and failure analysis

Hollow fiber bundle
Keyence Digital Microskope
3D view of the surface structure of a hollow fiber
Keyence image of a 3D printed turbine

  

REM picture of a hollowfiber
REM picture of a hollowfiber

  • OpenFOAM
  • ANSYS Fluent
  • CATIA
  • etc.
Cross section cardiac catheter pump
Example Simulation
Simulation turbine in green/blue with orange/red elements

Currently we use a Kudo 3D printer for parts with high resolution and biocompatible resin materials and a Markforged Mark Two printer for composite parts with high strength, stiffness and durability out of carbon fiber reinforced material, fiberglass and kevlar.

3D Print Turbine in white

  

A two component Laser Doppler Velocimetry (LDV) system (TSI Inc.) enables the accurate, pointwise measurement of fluid velocities and turbulence quantities.

LDV Setup

A 3D Particle Image Velocimetry System to visualize flowpatterns non intrusive

3D PIV setup with four cameras and a water tank