Timea Varadi from Department of Biophysics and Cell Biology of the University of Debrecen (Hungary) joins the lab again for 1 year. ErbB proteins play a significant role in the pathogenesis of a wide variety of human tumors. The significance of ErbB1 (EGFR), and ErbB2 is widely accepted, but much less is known about ErbB3. The associations of ErbB3 are important since they lead to the activation of the phosphatidylinositol 3-kinase (PI3K) pathway which worsens the prognosis of tumors. She is currently investigating the clustering of ErbB3, especially the quantitative aspects of these associations in quiescent and stimulated cells and by coexpression of ErbB2 receptors.
Timea Varadi joins the group as a postdoc